Transdermal Permeation of Kaempferia parviflora Methoxyflavones from Isopropyl Myristate-Based Vehicles
نویسندگان
چکیده
منابع مشابه
Xanthine oxidase inhibitory activities and crystal structures of methoxyflavones from Kaempferia parviflora rhizome.
Kaempferia parviflora (KP), a Zingiberaceae plant, is used as a folk medicine in Thailand for the treatment of various symptoms, including general pains, colic gastrointestinal disorders, and male impotence. In this study, the inhibitory activities of KP against xanthine oxidase (XOD) were investigated. The extract of KP rhizomes showed more potent inhibitory activity (38% at 500 µg/ml) than th...
متن کاملPharmacokinetics, bioavailability, tissue distribution, excretion, and metabolite identification of methoxyflavones in Kaempferia parviflora extract in rats.
Kaempferia parviflora (KP) is an herbal plant in the family of Zingiberaceae. KP mainly contains methoxyflavones, especially 5,7-dimethoxyflavone (DMF), 5,7,4'-trimethoxyflavone (TMF), and 3,5,7,3',4'-pentamethoxyflavone (PMF). The present study was designed to characterize the pharmacokinetics, including bioavailability, distribution, excretion, and identification of metabolites after administ...
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Kaempferia parviflora Wall. ex. Baker is a member of the ginger family (Zingiberaceae). In folk medicine of Suriname and Southeast Asia, rhizome is used for treatment of swelling, wounds and diarrhea colic disorder, and as an aphrodisiac (Yenjai et al., 2004). Rhizomes of fingerroot or K. parviflora Wall. ex. Baker are used as food ingredients and made into wine (Nagahara et al., 2002). Alcohol...
متن کاملSynergistic effect of isopropyl myristate and glyceryl monocaprylate on the skin permeation of pentazocine.
The aim of this investigation was to assess the applicability of lipid bilayer alteration using a combination of isopropyl myristate (IPM) and glyceryl monocaprylate (GEFA-C(8)) to the enhancement of pentazocine (PTZ) permeation through hairless mouse skin. The skin permeability of PTZ was enhanced by increasing the concentration of GEFA-C(8) up to 10% w/w in combination with IPM. Attenuated to...
متن کاملAnti-stress Effects of Kaempferia Parviflora in Immobilization Subjected Rats
It is well known that intense and prolonged stress can produce hippocampal neuronal damage and cognitive impairments, few studies have investigated possible ways to prevent its deleterious effects. Here, we investigated the neuroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, commonly known as Kra-Chai-Dum, on learning and memory loss and the induction of neur...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2014
ISSN: 1530-9932
DOI: 10.1208/s12249-014-0122-y